In this episode of "In the Interim…", Dr. Scott Berry details the design, execution, and results of the multi-platform randomized clinical trial (mpRCT) pioneered during the COVID-19 pandemic. He describes how REMAP-CAP, ATTACC, and ACTIV-4a—each developed independently—pooled data prospectively for joint analysis to address therapeutic anticoagulation in hospitalized COVID-19 patients. Scott outlines the operational rigor required to harmonize endpoints, establish monthly adaptive analyses, and stratify patients by disease severity and D-dimer level. He examines the unified Bayesian hierarchical modeling approach, dynamic borrowing across strata, and the process for simultaneous DSMB reviews coordinated across all platforms. The mpRCT framework enabled real-time, evidence-based adaptations and rigorous distinction of treatment effect by patient subgroup. Results were incorporated into clinical guidelines because prospectively specified analysis revealed benefit for moderate patients and futility or harm for severe patients—findings that would have been missed by standard post hoc pooling.Key HighlightsIntegration of REMAP-CAP, ATTACC, and ACTIV-4a under a prospectively unified analysis plan.Primary endpoint and stratified patient subgroups defined in advance.Monthly adaptive analyses using a shared Bayesian hierarchical model.Simultaneous oversight by joint statistical and DSMB committees.Superiority of therapeutic anticoagulation in moderate, non-critically ill groups; futility and possible harm in severe patients.mpRCT model established a framework for future global multi-platform trials.For more, visit us at https://www.berryconsultants.com/

In this episode of AWM Insights, Chief Investment Officer Justin Dyer and Portfolio Manager Mena Hanna dig into the hype and reality surrounding artificial intelligence and its impact on multi-generational wealth strategies. From the soaring valuations of data centers to the lessons hidden in recent market bubbles, they break down what families should know before investing in AI-driven trends. The conversation brings practical wisdom for long-term investors, highlighting when to tread cautiously, how to diversify effectively, and why the real winners might be the quieter “picks and shovels” businesses. Tune in for a timely, experienced perspective on navigating emerging technology cycles with your legacy in mind.Chapters(00:00) AI Hype and the Hundred-Year Family(01:00) Data Center Demand and Risks(03:31) Valuations, Bubbles, and Investor Caution(06:00) Lessons from High-Profile Speculation(07:52) Venture Capital Strategy and Diversification(10:56) Opportunity in Picks and Shovels Businesses(12:15) Public Markets and Managing ConcentrationConnect with Us• Call or text us: 626-862-0355• Website: https://www.athletefamilyoffice.com/• YouTube: https://www.youtube.com/channel/UCc1NxpK21N1vKWEExC45YEA• LinkedIn: https://www.linkedin.com/company/awmcapital/• Instagram: https://www.instagram.com/awmcapital/• X: https://twitter.com/awmcapital• Facebook: https://www.facebook.com/awmcapital/

Following on from last month's panel from Kennesaw State's Family Enterprise Center, Adam returns to have a conversation with Andrea Carpenter of The Transition Strategists. And this time they get practical: how to take a pulse on your life in the family company, the three questions every family member should keep asking, the headlines exercise that opened the door to Adam's own transition, and a LinkedIn story from a former CEO that shows the cost of an abrupt exit.Episode linksAndrea Carpenter: https://www.linkedin.com/in/andreakcarpenter/Your Next Gen Friend Podcast: https://open.spotify.com/episode/6QTytzkOKwGIEaOGRI5fec?si=fiANnFm_Sty0Ff78tgjnQAThe Transition Strategists: https://transitionstrategists.com/21C LinksTwenty One Clear website: https://www.21clear.comAdam Hatcher on LinkedIn: https://www.linkedin.com/in/adamhatcherSubscribe to the Twenty One Clear newsletter: https://21clear.substack.com/Bumper MusicStill Hot by Nic D, Connor Price | (c) Lossless, 2023Episode Produced Byhttps://snapmarket.coChapters[00:00] Welcome and Recap — Following up on Episode 11's Kennesaw State panel[02:00] My Thirteen Years and Why "General" Titles Drift[04:30] The Two Roots: Open Dialogue and Twenty Years of Family Meetings[07:00] If You've Never Held a Family Meeting, Start Here[09:30] Opening the Door When You're the Next Generation[12:00] "Build a Great Company With a Strong Family" — The Opening Line[14:30] Andrea on Who Starts the Conversation[17:00] The Three Questions Every Family Member Should Ask[20:00] Engagement Isn't Automatic — Reward, Recognition, and Development[23:00] Andrea's Objectives Matrix and Defining Your Deal Breakers[25:30] The Headlines Exercise: How I Stepped Out of My Roles[28:00] Pete's Story From LinkedIn — The Cost of an Abrupt Exit[29:30] Closing — How to Keep Thinking About Your Inner Family Business

Join us for a behind-the-scenes look at how execution drives returns in industrial real estate development. Paul Bennett sits down with Shawn Beichler, AAA Storage’s Director of Development and Construction, to break down the project lifecycle—from land acquisition and permitting to custom tenant build-outs. Discover how AAA Storage’s hands-on approach, local expertise, and focus on flexibility create lasting value for both tenants and investors. If you’re curious about how real results are built from the ground up, this episode is packed with practical insights you won’t want to miss.Ready to talk about your investment strategy? Reach out at aaastorageinvestments.com New episodes every two weeks. Subscribe on Apple Podcasts, Spotify, or wherever you listen to podcasts, and send this to an investor in your network who needs to hear it. Chapters(00:00) Development Leadership and Experience(03:00) Project Lifecycle and Key Processes(06:00) Unique Construction and Integration Approach(10:00) Custom Tenant Finish-Outs(12:00) Execution and Risk Management(17:00) Permitting and Civil Engineering Challenges(27:00) Flexibility, Market Experience, and Investor AdvantagesWe believe good investing starts with a conversation, so if today's episode got you thinking about your investment strategy, reach out to us through our Contact Form and let's start building together: https://www.aaastorageinvestments.com/contactFollow and Connect with Us• LinkedIn: https://www.linkedin.com/company/aaa-storage-investments/• Instagram: https://www.instagram.com/aaastorageinvestments/• X: https://x.com/investments_aaa• Facebook: https://www.facebook.com/people/AAA-Storage-Investments-LLC/61575027573292/Download our free guides to take your investing to the next level:10 Due Diligence Questions to Vet Any Real Estate Sponsor: https://www.aaastorageinvestments.com/info/10-due-diligence-questions-to-vet-any-real-estate-sponsorFirst-Time Real Estate Syndication Investor Checklist: https://www.aaastorageinvestments.com/info/first-time-real-estate-syndication-investor-checklist

In this heartfelt solo episode, Pastor Josh shares a personal journey of discovering the transformative power of prayer, emphasizing its role in intimacy with Jesus, spiritual growth, and effective ministry. Learn practical steps to deepen your prayer life and experience God's presence more fully.Chapters00:00 Introduction: The Heart of Prayer00:31 Planting Seeds: The Hidden Work of Ministry01:55 Why Attendance Doesn't Define Success02:49 Fruit from Intimacy with Jesus03:42 Making Prayer a Personal Commitment04:11 Deciding to Make Prayer a Priority in 201805:07 Establishing a Daily Prayer Routine07:01 Experiencing God's Presence in Prayer08:54 Prayer as Refuge in Difficult Times09:48 Prayer as the Source of Life and Power10:47 The Holy Spirit and Power for Ministry11:56 The Love of God and Its Impact12:55 The Secret Place and God's Rewards13:57 The Goal of Prayer: Simply Be with God15:17 Practical Tips to Start and Grow Your Prayer Life16:40 The Supernatural Rewards of Prayer19:26 The Fruit of Prayer: Calling and Purpose22:08 The Impact of Prayer on Evangelism and Power23:34 Encouragement to Prioritize Prayer24:28 Starting Small: Five Minutes of Silence25:52 Extended Prayer: Going Beyond the Comfort Zone26:49 Accessing All God Has for You in Prayer